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elegans model, urolithin A activates the AMPK signaling pathway and significantly promotes mitophagy, which prolongs lifespan by 45.4%

Andersen et al., Low Activity Of Superoxide Dismutase and High Activity of Glutathione Reductase in Erythrocytes from Centenarians, Age Ageing 27 (5), 643648 (1998)

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Compromised autophagy and neurodegenerative diseases

doi: 10.3390/molecules26164998 51 ElhawaryEAMoussaAYSingabANB