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GLP-1 directly regulates insulin secretion, while GLP-1 RAs have the potential to improve insulin sensitivity and glucose homeostasis by attenuating inflammatory pathways such as NF-B and the NLRP3 inflammasome signaling, thereby mitigating IR [40]

Asimismo, puede causar trastornos del sueo si se ingiere menos de 6 horas antes de irse a dormir

Nonetheless, in patients receiving anticoagulants or antiplatelet agents, high-dose EPA formulations warrant enhanced monitoring to mitigate potential additive bleeding risk

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In conclusion, these data show that the overactivation of the sympathetic nerve under obese conditions is closely related to ferroptosis of the vagus nerve and the parasympathetic nervous system

All animal procedures were conducted in strict accordance with the Guide for the Care and Use of Laboratory Animals published by the U.S