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For most persons with wheatish to dark skin, Vitamin C tablets may be sufficient

Significant brightening and glow enhancement typically appear after 6-8 weeks

However, improper usesuch as increasing the dosage too quicklycan reduce its effectiveness and lead to negative side effects

Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli

Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D et al (2003)