Hartwell et al (104) observed that CD8+ tumor-infiltrating T cells, under hypoglycemic and hypoxic conditions, alter the metabolic profile of tumor cells from glycolysis to fatty acid catabolism, thereby sustaining the energy supply and stemness characteristics of tumor cells
However, data are scant and controversial, resulting in limited efforts to study the effect of nutritional interventions on GSH status
The large heterogeneity for some outcomes, such as CAD, may suggest different mechanisms underlying the genetic associations or the existence of pleiotropy [37]
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Naunyn Schmiedebergs Arch Pharmacol 394(11):21972222 Iskusnykh IY, Zakharova AA, Pathak D (2022) Glutathione in brain disorders and aging
Adv Immunol 121:91119