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Spatial and temporal variability in edaphic properties, microbial assemblages and microclimatic conditions reprogram transcriptional regulation, metabolic networks and phenotypic plasticity, often modifying responses inferred under controlled environments

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The DREAMS-3 data showing superiority over semaglutide for the dual endpoint of glycemic control and weight loss makes mazdutide particularly attractive for the diabetes population

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10.1016/j.pharmthera.2017.06.001 139 LuY.CaoD.-L.JiangB.-C.YangT.GaoY.-J