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Biochemistry , 38(20): 6699-6705 Coles, B

In Phase 2 clinical trials, the safety profile was broadly consistent with other incretin-based therapies, with gastrointestinal side effects being the most commonly reported

Our understanding of the disease mechanisms and molecular targets of drugs has been facilitated by new biotechnology advances, such as RNA sequencing

Innovations in Clinical Neuroscience, 15 (3-4), 2832

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On the other hand, aging, genetic predisposition, and persistent oxidative stress can all hinder Nrf2 activation in microglia, allowing for prolonged NLRP3 activity and sustaining the inflammatory cycle [63]