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TUNEL assay On experimental day P38, pancreas samples were fixed in 2% w/v paraformaldehyde for 2 h and processed for TUNEL assay, which was performed using the One Step TUNEL Apoptosis Assay Kit (Beyotime, Shanghai, China) according to the manufacturers instructions
45,46 GLP-1RAs GLP-1RAs result from intricate structural modifications to GLP-1, enabling them to not only replicate the pharmacological functions of GLP-1 but also impede its hydrolysis by DPP-4, thereby extending the drugs half-life
This includes proton pump inhibitors, H2 receptor antagonists, metformin, certain antibiotics, and chemotherapy agents
PhamVFehlbaumSSeifertNRichardNBruinsMSybesmaWet alEffects of colon-targeted vitamins on the composition and metabolic activity of the human gut microbiome- a pilot study
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