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This is usually temporary and can be managed by adjusting the dosage or ceasing use

Store lyophilized vials in the original amber glass or dark packaging, away from any direct or indirect light source including natural window light

For users that experience these side effects, your provider may suggest spacing out dose escalations even further (for example, increasing your dose every 6-8 weeks instead of every 4 weeks)

Dysbiosis, or microbial imbalance, is believed to disrupt this axis, leading to alterations in gut motility, pain sensitivity, and immune responses, which are common in conditions like IBS and IBD

This is correlated with increased endothelial inflammation, characterized by intercellular adhesion molecule 1 expression, and enhanced endothelial senescence at the molecular level

Open bottles are usable for at least 90 days after opening