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Signs of severe dehydration including very dark urine, dizziness upon standing, or rapid heart rate

Taken together, GLP-1, inflammation, and the gut microbiota form a tightly interlinked feedback loop

In early human trials, some individuals showed reduced alcohol cravings and lower intake

Through enhanced pharmacokinetic profiles, once-weekly GLP-1RA injections, notably semaglutide, are becoming increasingly popular in the treatment of T2DM

Therefore, BMP4 becomes a potential therapeutic target in CRC, especially in a diabetic context where high blood glucose significantly affects cancer progression through the BMP4 pathway

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