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The tubular protective effects appeared to be associated with the counteraction of PPAR deterioration, resulting in a maintenance of FAO, a decrease of intracellular accumulation of undigested FFAs, and attenuation of disease developmental factors including oxidative stress, apoptosis, and NFB activation (Takahashi et al., 2011)

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

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KstnerNRichterSHUrbanikSKunertJWaiderJLeschKPet al