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This triggers the MAPK cascade, such that Ras-GTP activates Raf [also called MAPK kinase kinase (MAPKKK)], which in turn activates MEK1/2 [MAPK kinase (MAPKK)]

Injection-site reactions are mild and infrequent

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Hif1 mRNA expression did not differ between the control and mutant mice although the initial level of Hif1 expression was higher in the WT livers than in the Gstp1/2 / livers (Figure 7a)

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The pathogenesis of polycystic ovary syndrome (PCOS): The hypothesis of PCOS as functional ovarian hyperandrogenism revisited