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The prognosis and treatment options depend on: the thickness of the tumor and where it is in the body whether there was bleeding or ulceration of the tumor how much cancer is in the lymph nodes the number of places and where cancer has spread to in the body the level of lactate dehydrogenase (LDH) in the blood whether the cancer has certain mutations (changes) in a gene called BRAF your age and general health Stages of Melanoma Key Points The stage of melanoma depends on the thickness of the tumor, whether cancer has spread to lymph nodes or other parts of the body, and other factors

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doi:10.1080/14992027.2021.1964040.

That said, the strongest test of a circulation claim intermittent claudication, or leg pain from reduced blood flow when walking came back negative in the 2013 Cochrane review: no statistically significant improvement in pain-free walking distance vs placebo across pooled trials[7]Ginkgo for Intermittent Claudication Cochrane View source