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By acting directly on fat tissues, it helps achieve weight loss in specific areas without systemic side effects

Biol Chem 390:191-214

Semaglutide consistently reduces triglycerides, a direct consequence of reduced caloric intake and improved insulin sensitivity

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However, the test subjects did experience the following minor side effects: Mild injection site reactions (pain, itching, swelling) Headaches Diarrhea, Hypertension Induration CJC-1295 administration has also been linked to mild, transitory side effects such as flushing, water retention, and insomnia [7]