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The activation of this pathway is characterized by the upregulation of pro-apoptotic proteins such as Bax, inhibition of anti-apoptotic proteins like Bcl-2, and the release of Cyt-c from mitochondria into the cytosol [73, 161]

Ante este panorama, todos los posibles recursos teraputicos deben ser considerados para enfrentar el sobrepeso y la obesidad, desde el ejercicio fsico hasta nuevos productos farmacuticos

doi: 10.1002/jppr.1953