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Injecting too shallow (intradermal) or too deep (intramuscular) can affect absorption rates and pharmacokinetics

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(1) Laferrre B, Abraham C, Russell CD, Bowers CY

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Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times