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By Q3 2025, Zepbound held 71% of all new US obesity prescriptions , having overtaken semaglutide (Wegovy) as the dominant choice for weight management

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Switching between GLP-1RA medications should be viewed as a normal part of long-term obesity care, said senior author Sarah Messiah, Ph.D., M.P.H., Professor of Epidemiology and Pediatrics, Associate Dean for Research in the ODonnell School of Public Health, and Director of the Child and Adolescent Population Health Program