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Comorbidity Coding E11.40 is frequently coded alongside other diabetes complications and comorbidities, including acute presentations such as hyperosmolar hyperglycemic state when a neuropathy patient is admitted in metabolic crisis

VK2735 demonstrated encouraging safety and tolerability following 13 weeks of once-weekly dosing in the Phase 2 VENTURE study

Bs team

PMID 12814619

Key mutations in genes such as C24SMT, C5DS, and C14DM lead to the loss of ergosterol and the accumulation of other sterol precursors, which reduce the binding affinity of AmB to the parasite membrane and decrease drug sensitivity (Mukherjee et al., 2020)

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