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doi: 10.1172/JCI127277 26 LeeHYoonY

In contrast, cAMP signaling in response to GLP-1 was comparable between wild-type and mutant receptors, supporting the hypothesis that altered signaling with PF-06882961 was not due to a marked alteration of surface expression for the mutated constructs (Fig

Some patients request lipo c refills because 'they felt more energetic' on prior doses

Participants who experienced significant nausea, vomiting, or other gastrointestinal symptoms during escalation could have their dose increase paused or delayed until symptoms resolved

In other cases, mucosal or cutaneous symptoms may be a part of the initial presentation [49, 50]