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It is also not recommended to use Januvia in combination with a GLP-1 agonist drug such as Ozempic because there is no added benefit due to their redundant mechanisms of action

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The blend remains a subject of experimental interest for researchers studying musculoskeletal, cardiovascular, gastrointestinal, and neurological healing processes

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Preclinical and clinical studies suggest that activation of GLP-1 receptors may attenuate reward-related responses, providing a biologically plausible mechanism through which GLP-1RAs could affect nicotine dependence (22)

doi:10.1055/s-2000-7972