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MPV measures the average size of your platelets

This means that as well as beta-1 receptors in the heart it also blocks beta-2 receptors in the bronchioles (airways), which can cause a narrowing of the bronchioles and breathing difficulties in people with pre-existing lung disease

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This explains why comparative side-effect studies show such wide rangesthey don't account for individual genetic predisposition to GI intolerance

Additionally, because GLP-1 receptors are present in the brain regions involved in regulating sleep, Semaglutide might have an indirect impact on sleep patterns

[2] Samiec, P