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Results Between 10 and 20 mg/kg dose, median AUCs of acetaminophen, glucuronide, sulfate, and cysteine increased significantly resulting in unchanged ratios of AUC of metabolite to acetaminophen

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This reverses endothelial cell senescence and promotes angiogenesis via the MAM-mediated mitochondria-senescence axis (Xian et al., 2024)

As a signaling molecule, -KG directly interacts with certain proteins to regulate compensatory glucose uptake or modulate CaMKK2 kinase activity under different stress conditions 21,22