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Freezing after reconstitution is a different question

Maintaining weight loss during the switch Weight maintenance during the switching period requires deliberate strategy

FDA (2022) FDA revises labels of SGLT2 inhibitors for diabetes to include warnings about too much acid in the blood and serious urinary tract infections

however, approximately 2.6% to 3.2% of DKA admissions are cases of EDKA, in which metabolic acidosis and ketoacidosis are accompanied by euglycemia

Overall, the combination of these effects makes semaglutide an effective tool for weight loss in adults with obesity or overweight