Batchuluun B, Inoguchi T, Sonoda N, Sasaki S, Inoue T, Fujimura Y, Miura D, Takayanagi R: Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD(P)H oxidase pathway in human aortic endothelial cells
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Furthermore, AMPK suppresses reactive oxygen species (ROS) production at its source by inhibiting membrane assembly of NADPH oxidase (NOX) and reducing xanthine oxidase (XO) activity
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Upregulated ID3 interacts with E47 to decrease its interaction with the promoter region of CDH1 and prevent the repressive effects of E47 on CDH1 transcription, maintaining E-cadherin transcription and the epithelial phenotype of PTC [99]