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El gran problema de estos frmacos es que no diferencian entre grasa y msculo, lo que aumenta el riesgo de sarcopenia, es decir, fragilidad, prdida de masa muscular y peor calidad de vida, sobre todo en pacientes de edad avanzada (25)
Pregnant or breastfeeding women and individuals with specific health conditions should consult their doctor before starting
Pharmaceutical companies have developed longer-acting versions of GLP1s, which have been shown to be effective in treating diabetes and obesity, but there is still a need for guidelines on the long-term use and potential tapering off of the medication 6m0s
GLP-1 medications like semaglutide directly influence glucose metabolism, appetite regulation pathways, and lipid handlingall measurable through standard laboratory tests
In ob/ob obese mice, a low iron diet or iron chelation therapy protected against -cell failure and insulin resistance and lowered triglycerides, but these effects were not replicated in healthy weight mice [38]
