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Obesity is one of the biggest health concerns, killing more than 2.8 million people every single year [1]

These interactions highlight the complex and integrated role of gut-derived peptides in modulating cardiovascular function, emphasizing the therapeutic potential of targeting these pathways in cardiovascular diseases as captured below under gaps and new areas of investigation

CNS brain neurons are mainly fueled by glucose metabolized through OXPHOS

Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia)

This fermentation, though less extensive than with other fibre types, can produce short-chain fatty acids (SCFAs) such as butyrate, propionate, and acetate, which may stimulate L-cells in the colon to secrete GLP-1

2017 Feb;95(2):206-214