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However, several uncontrolled observational studies have reported improvement in both motor and non-motor symptoms after taking cannabinoids, including reduced rest tremor, bradykinesia, rigidity, and levodopa-induced dyskinesia (LID), as well as improved pain, depression, psychosis, hallucinations, orientation, symptoms of RBD, and sleep quality [65]

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[DOI] [PubMed] [Google Scholar] Mezey E, Eisenhofer G, Hansson S, Harta G, Hoffman BJ, Gallatz K, Palkovits M, Hunyady B (1999) Non-neuronal dopamine in the gastrointestinal system