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L-carnitine deficiency severely impairs the mitochondrial import of long-chain acyl-CoAs, directly limiting the acetyl-CoA pool required for ketogenesis ( -oxidation activity ( Figure 2 The preterm brain exhibits extraordinarily high energy demands to fuel rapid growth and development, demands which can surpass the capacity of glucose supply alone

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Manufacturers fund large programs that address access barriers around approved products

Alexander HC, Nccarty WN, Bartlett EA

Up to 24.2% body weight reduction over 48 weeks

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