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It was known as the endogenous ligand for the growth hormone secretagogue receptor (GHSR)

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This study investigated the effects of metformin and chloroquine on the efficacy of cytarabine in NALM-6 cells

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J Biotechnol 279:5560

49,50 G6PD or PGD depletion significantly decrease NADPH levels and enhance chemotherapeutic drugs-induced cell apoptosis by redox modulation