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Identification of ferroptosis-related hub genes and their association with immune infiltration in chronic obstructive pulmonary disease by bioinformatics analysis

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13 In the CVOTs, GLP-1 RAs were associated with a reduction in new-onset HF among patients with cardiovascular risk factors, but neutral effects were observed on HF events among patients with already diagnosed and stable HF

Binding of VP24 to Keap1 Kelch domain releases Nrf2 from Keap1-mediated inhibition, promoting persistent activation of diverse cytoprotective genes implicated in cellular responses to oxidative stress and regulation of inflammatory responses

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Conclusion GLP-1 receptor agonists, regardless of structure, have beneficial effects on body weight and fat content in type 2 diabetes with sarcopenia, but have no effect on reducing muscle mass