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The study found that C-X-C motif chemokine ligand 10 (CXCL10) and its receptor CXCR3 play key roles in regulating the infiltration of CD8+ T cells into the brain, and the infiltrated CD8+ T cells appear to interact with microglia to jointly promote ADs neurodegeneration

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Carnitine is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.[1] In eukaryotic cells, it is required for the transport of fatty acids from the intermembraneous space in the mitochondria, into the mitochondrial matrix during the breakdown of lipids (fats) for the generation of metabolic energy.[2] It is widely available as a nutritional supplement

Our previous research indicated that overexpression of SREBP2 leads to increased expression of GLUT1/6 [6]

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