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The competitive advantage of GHK-Cu lies not in marketing hyperbole but in its broad transcriptional reach modulating over 4,000 genes linked to wound healing, oxidative stress resistance, and extracellular matrix homeostasis

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It inhibits GSH depletion, GPX4 degradation and lipid peroxidation, increases Nrf2, and inhibits 12/15-LOX (Xie et al., 2016