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This receptor activation triggers melanin synthesis through the cyclic AMP signaling cascade

Glutathione deficiency may promote cancer initiation (by failing to protect DNA from oxidative damage), while elevated glutathione in established tumors may promote cancer progression and treatment resistance (by protecting cancer cells from chemotherapy and radiation) [2][5]

Rubinow DR, Peck GL, Squillace KM, et al

A 250 mcg dose is 0.1 mL, or 10 units on a U-100 syringe

A double-blind, randomized trial of 151 patients with ovarian cancer found that intravenous glutathione therapy reduced the toxicity of cisplatin and improved quality of life