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Drug discovery and development for the CNS typically involves in silico screening followed by in vitro assessment of permeability and toxicology, animal studies, and human trials 2
doi:10.1186/s13148-015-0132-y
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"Peptide-Based Approaches to Appetite Control: Comparative Mechanisms of Amylin and GLP-1 Analogs." Appetite, 178, 106182
Interest in DSIP research declined over time, partly because of mixed clinical findings and partly because peptide research funding shifted toward other compounds