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Use a properly sized syringe with a 30-31 gauge needle, 4-6mm in length, for maximum comfort

General handling: Always replace the pen cap after each use to protect from light and maintain sterility

One telehealth provider reported their compounded semaglutide tolerates temperatures up to 95 degrees Fahrenheit for a maximum of 4 days, and up to 77 degrees for 15 days

Discard 28 days after first puncture

Slower Adjustment to Appetite and Digestive Changes Some patients describe a preference for gradual changes rather than rapid shifts in hunger or digestion