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The advantage of Nrf2-Keap1 PPI inhibitors is improved target selectivity

Each workout produces an acute burst of reactive oxygen species (ROS) in muscle, which paradoxically triggers the cell's defense mechanisms a phenomenon known as mitohormesis ( 3.3 Physical capacity and metabolic health The systemic benefits of exercise in older adults extend to muscle strength, endurance, and metabolism

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doi: 10.1515/cclm-20110817 179 Sengul SamanciNPoturogluSSamanciCUstabasiogluFEKoldasMDumanAEet al