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These demonstrated short-term safety in adults with normal renal and hepatic function

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While healthy kidneys can flush out excess B12 since its water-soluble, those with impaired kidney function might struggle to eliminate it, leading to unwanted buildup in the blood

While a lack of genetic association does not exclude therapeutic potential, it lowers confidence when other indicators are weak

Some more stable peptides can last 4-6 weeks, while fragile ones may show significant degradation by week 2