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The intracellular concentration of glutathione (GSH) in tumor cells, ranging from 2 to 10 mmol/L, exceeds that of the extracellular concentration by over 1000-fold (2 to 10 mol/L), and is also four times greater than the GSH concentration found in normal cells 35

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doi: 10.1186/s40246-023-00561-w 7 DieterichWSchinkMZopfY

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Inositol's bioavailability drops

Therefore, the tissue-specific effects of l-carnitine are likely to be different among species, and thus more low-carnitine animal models should be established to intensively evaluate the possible different functions of l-carnitine among species