For example, PLP is required for the synthesis of neurotransmitters such as GABA and serotonin, for heme biosynthesis (through -amino levulinate synthase in red blood cell production), and for amino acid transformations
Pyo et al., Arch Pharm Res, 2007)
Here is a practical guide: 5mg vial: Add 1mL of bacteriostatic water for a concentration of 5mg/mL (5,000mcg/mL)
Storage: Store in a cool, dry place away from direct sunlight
Methylcobalamin 10 mg Injectable Product ID: 5185815 Brand: Hallandale Pharmacy Form: Injectable Size: Lyophilized In 10 mL Vial Concentration: Requires Reconstitution Strength: 1 mg/mL Description: Red Powder, Red Solution Reconstituted Package: Amber Glass Vial Schedule: Rx Only Route of Administration: Intramuscular Subcutaneous IV infusion Appearance: Our Injectable Methylcobalamin comes as a lyophilized (freeze-dried) red powder, reconstituted into a red injectable solution
Nonetheless, as mentioned above, the hypovascular nature of the connective tissues makes it challenging to utilize the fundamental building blocks of the bloodstream