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Mitochondria perform diverse yet interconnected functions, generating ATP and many biosynthetic intermediates that support neuronal homeostasis and reduce cellular stress responses such as autophagy and apoptosis [133]

Further characterization of metabolite compartmentalization and associated enzymatic activity revealed that blood NADs and glutathione predominantly reside within cellular fractions, with plasma containing only trace amounts of NADH and no detectable glutathione (Fig

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Topical application offers limited penetration for deep spinal structures

BPC 157 has also been found to counteract both vein hypertension and arterial hypotension in rat interior vein ligature model 33

For NPs of similar size and composition, their shape of NPs can alter their biological activities, including biodistribution, cellular uptake, deposition, and clearance (Zare et al., 2021)