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The authors concluded it appears effective and generally safe

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Our results also demonstrated that WECP promoted the transcription and translation of -Catenin and Wnt10b, induced DPCs growth, and upregulated Wnt5a and LEF1 in mouse dorsal skin (Figures 4, 5)

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doi: 10.1039/c3ib40126j 145 ParkSEGeorgescuAHuhD

Managing Morning Pain: Night Positioning and Behavioral Strategies Morning pain is often the sharpest due to overnight plantarflexion and fascial shortening