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Because injected GH activates the same negative feedback that somatostatin mediates, prolonged exogenous HGH administration blunts the pituitary's own production

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Interestingly, recent reports suggest that appendectomies lowered PD risk, while individuals with an intact vermiform appendix showed increased levels of truncated soluble -synuclein, capable of oligomerization and propagation (Killinger et al., 2018)

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