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Abbass NJ, Nahlawi R, Shaia JK, Allan KC, Kaelber DC, Talcott KE, et al

Toxins 13:252

Reporting is voluntary [19]

Small molecule inhibitors targeting key enzymes of lipid synthesisincluding firsocostat (Acetyl-CoA Carboxylase inhibitor), TVB-2640 (Fatty Acid Synthase inhibitor), and aramchol (Stearoyl-CoA Desaturase-1inhibitor) have shown efficacy in reducing hepatic fat accumulation and indirectly attenuating HSC activation

Safety and Tolerability Considerations: Tricyclic Antidepressants vs

Histological examination with HE and PAS staining showed glomerular cell proliferation, enlargement of the mesangial matrix, and increase in the thickness of the basement membrane, confirming the proper establishment of the DKD model (Figure 3A)