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Data from a large, randomized clinical trial named SELECT indicate cardiovascular protective benefits from taking the GLP-1 weight loss therapeutic Wegovy (semaglutide) for a sub-population with preexisting cardiovascular disease

Cost Over 6 Months: Scenario Analysis To understand the total financial commitment, here are 6-month cost scenarios based on Yucca's published pricing structure: Yucca Health Compounded Semaglutide (6-month plan): First month: $146 Months 2-6: $206/month 5 = $1,030 6-Month Total: $1,176 Yucca Health Compounded Tirzepatide (6-month plan): First month: $258 Months 2-6: $325/month 5 = $1,625 6-Month Total: $1,883 Brand-name medications can be significantly more expensive without insurance coverage

Aim for at least 8 glasses of water per day and consider adding electrolytes

Notably, treatments with the multi-agonists or GLP1 did not cause signs of nausea/malaise at any time-point tested (272 h), since pica behavior (i.e., kaolin intake) was similar, or even lower, in mice treated with GLP1/E, GLP1/GIP, GLP1/GIP/Glucagon, or GLP1 vs

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These medications carry a boxed warning about thyroid C-cell tumors (contraindicated with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2) and warnings about potential risks including pancreatitis, gallbladder disease, acute kidney injury with dehydration, and worsening diabetic retinopathy with rapid glucose reduction (particularly with semaglutide)