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Name: glp 1 rebound weight gain Stopping GLP-1s: Regain and Maintenance Tips Reverse The Rebound Weight Gain
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PMID: 37366315 | doi:10.1056/NEJMoa2301972 Rosenstock J et al

& Zinsmeister, A

What they found: Dose-dependent stimulation of type II collagen (up to 2.5 baseline at 100 nM) Stimulation of aggrecan (up to 1.8 baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis