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Here, we demonstrated that long-term oscillating glucose challenge in vivo resulted in desensitization of insulin secretion due to -cell mass exhaustion, which was caused by -cell dedifferentiation

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MT,one of the hormones secreted by the pineal gland in the brain, has strong neuroendocrine immune regulatory activity and the ability to scavenge free radicals and act as an antioxidant

R., Barbieri, M., Marfella, R

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