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Most people don't wake up one morning and think, "I've lost 12 pounds of muscle." Instead, the signs appear gradually: Carrying groceries feels harder Climbing stairs becomes more difficult Your balance isn't quite as steady You tire more easily during exercise Your strength plateaus or declines By the time those changes become obvious, muscle loss may have been occurring for months

More studies challenge the traditional opinion that BECs are indolent and passive barrier cells in BBB Recent technical advances such as single-cell sequencing have helped us notice the crucial roles of BECs in neurodegenerative diseases

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