The mechanism of action involves appetite suppression, delayed gastric emptying, and improved insulin sensitivity
Factors that influence your personal calorie needs include: Current body weight and composition heavier individuals typically require more calories Age metabolic rate generally decreases with age Physical activity level more active individuals need additional calories Medical conditions certain health issues affect metabolic requirements Medications some drugs influence metabolism and appetite Whilst some general guidelines suggest minimum intakes of around 1,200 calories for women and 1,500 calories for men, these are not evidence-based for all individuals and may be inappropriate for many people
Much remains unknown about the long-term effects of current weight loss medications, with even less known about how the drugs will impact sleep
doi: 10.1038/s41416-020-01156-1 55 SchiliroCFiresteinBL
For most patients, these symptoms are transient and manageable, but they emphasize the need for gradual dose escalation and patient education on managing side effects
doi:10.1021/acs.jmedchem.1c00565 Cao J, Belousoff MJ, Johnson RM, et al
