Collectively, these findings highlight the potential of amino acids such as arginine, proline, glutamate, methionine, cysteine, glutamine, and BCAAs as novel biomarkers for IPF diagnosis, disease staging, and progression monitoring
in fact, some clinical evidences suggest it may have a potential protective effect in reducing lung cancer risk
In breast cancer cell lines (MCF-7), activation of IGF/PI3K signaling enhances mitochondrial homeostasis by increasing the number of new mitochondria and levels of oxidative phosphorylation and promotes the degradation of damaged mitochondria (mitochondrial autophagy) by increasing BNIP3, a protective mechanism that ultimately influences the cancer treatment response and evolution of the cancer phenotype (53)
2006 Dec;91(12):5013-8
Blom, A
Moreover, both the inflammation of microglia in the motor cortex and spinal cord of ALS patients and the expression of IDO and QA in neuronal cells and microglia increased significantly