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More notably, substantial CD8 + T-cell infiltration and aberrant PD-L1 signaling have been observed in AD brain tissues, suggesting the presence of a locally immunosuppressive microenvironment
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Furthermore, NaBPC157 reduced MPTP-motor abnormalities (tremor, akinesia, catalepsy, otherwise very prominent in saline control) leading to an almost complete abolition of the normally lethal course of MPTP treatment in controls
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