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This work was supported by the National Natural Science Foundation of China (81790640, 32070989, 31872766, 31571075, 82070993, and 31571072), the Ministry of Science and Technology of China (2011CB504602 and 2015AA020512), Shanghai Municipal Science and Technology Major Project (2018SHZDZX01), ZJLab, Shanghai Center for Brain Science and Brain-Inspired Technology, and Sanming Project of Medicine in Shenzhen (SZSM202011015)

For patients with significant portal hypertension or ascites, deltoid or lateral thigh injection sites avoid the potentially altered abdominal vascular dynamics

The frequency and severity depend on the specific compound, exposure, titration approach, and patient

We focus on achieving long-term results while maintaining the highest standards of patient care

10.1371/journal.pone.0061054 PLoS One 27 Di RenzoM